The main interest of our laboratory is to achieve a better understanding of the cellular and molecular processes that contribute to aging and the impact that nutrition has on them. To study the impact that elements of our diet have on the pathophysiology of tissues and organs we use a variety of cellular and animal models.

When the body ages or is under pathological stress, there is an accumulation of damaged proteins, as well as a loss of communication between the cells that make up our tissues. In our laboratory we are focused on the study of these 2 altered processes during aging and diseases associated with aging: loss of proteostasis (due to deficient function of cellular waste recycling systems) and loss of intercellular communication in our tissues. We explore how alterations in these cellular processes can contribute to aging and aging-related diseases, with a special emphasis on ocular and neurodegenerative diseases.

A better understanding of these processes will help us identify compounds and develop strategies that will result in new therapies to fight these human diseases and promote healthy aging.