Our main goal is to gain more in-depth knowledge of the new concept of cysteine-related molecules involved in cell signaling of essential processes for plant development. Thus, we are focused on the role of cysteine-generated sulfide as a signaling molecule that regulates autophagy, the mechanism of action and sulfide specific targets for persulfidation.

We have recently demonstrated that ATG4a and ATG18a are sulfide-mediated persulfidated in specific cysteines, regulating the progress of autophagy.